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  • Senior Research Fellow, Baker IDI Heart and Diabetes Institute

Research interests

  1. Type 1 Diabetes
  2. Regenerative Medicine
  3. Reprogramming progenitor and adult cells into insulin secreting cells.

Publications

  1. Al-Hasani K, Pfeifer A, Courtney M, Ben-Othman N, Gjernes E, Vieira A, Druelle N, Avolio F, Ravassard P, Leuckx G, Lacas-Gervais S, Ambrosetti D, Benizri E, Hecksher-Sorensen J, Gounon P, Ferrer J, Gradwohl G, Heimberg H, Mansouri A, Collombat P. Adult Duct-Lining Cells Can Reprogram into β-like Cells Able to Counter Repeated Cycles of Toxin-Induced Diabetes. Dev Cell. 2013 Jul 15;26(1):86-100.
  2. Hatfaludi T, Al-Hasani K, Gong L, Boyce JD, Ford M, Wilkie IW, Quinsey N, Dunstone MA, Hoke DE, Adler B. Screening of 71 P. multocida proteins for protective efficacy in a fowl cholera infection model and characterization of the protective antigen PlpE. PLoS One. 2012;7(7):e39973.
  3. Courtney M, Pfeifer A, Al-Hasani K, Gjernes E, Vieira A, Ben-Othman N, Collombat P. In vivo conversion of adult α-cells into β-like cells: a new research avenue in the context of type 1 diabetes. Diabetes Obes Metab. 2011 Oct;13 Suppl 1:47-52. doi: 10.1111/j.1463-1326.2011.01441.x. Review.
  4. Hatfaludi T, Al-Hasani K, Boyce JD, Adler B. Outer membrane proteins of Pasteurella multocida. Vet Microbiol. 2010 Jul 29;144(1-2):1-17. doi: 10.1016/j.vetmic.2010.01.027. Epub 2010 Feb 4. Review.
  5. Al-Hasani K, Navarro-Garcia F, Huerta J, Sakellaris H, Adler B. The immunogenic SigA enterotoxin of Shigella flexneri 2a binds to HEp-2 cells and induces fodrin redistribution in intoxicated epithelial cells. PLoS One. 2009 Dec 9;4(12):e8223. doi: 10.1371/journal.pone.0008223.
  6. Hatfaludi T, Al-Hasani K, Dunstone M, Boyce J, Adler B. Characterization of TolC efflux pump proteins from Pasteurella multocida. Antimicrob Agents Chemother. 2008 Nov;52(11):4166-71. doi: 10.1128/AAC.00245-08. Epub 2008 Aug 25.
  7. Myers GS, Parker D, Al-Hasani K, Kennan RM, Seemann T, Ren Q, Badger JH, Selengut JD, Deboy RT, Tettelin H, Boyce JD, McCarl VP, Han X, Nelson WC, Madupu R, Mohamoud Y, Holley T, Fedorova N, Khouri H, Bottomley SP, Whittington RJ, Adler B, Songer JG, Rood JI, Paulsen IT. Genome sequence and identification of candidate vaccine antigens from the animal pathogen Dichelobacter nodosus. Nat Biotechnol. 2007 May;25(5):569-75. Epub 2007 Apr 29.
  8. Al-Hasani K, Boyce J, McCarl VP, Bottomley S, Wilkie I, Adler B. Identification of novel immunogens in Pasteurella multocida. Microb Cell Fact. 2007 Jan 18;6:3.
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